{"id":5212,"date":"2011-07-14T20:24:27","date_gmt":"2011-07-14T20:24:27","guid":{"rendered":"http:\/\/crashtext.org\/misc\/stress-ulcers.htm\/"},"modified":"2014-07-15T18:16:45","modified_gmt":"2014-07-15T22:16:45","slug":"stress-ulcers","status":"publish","type":"post","link":"https:\/\/crashingpatient.com\/intensive-care\/stress-ulcers.htm\/","title":{"rendered":"Stress Ulcers and GI Prophylaxis"},"content":{"rendered":"<p>Stress Ulcers Loss of protective barrier in the stomach of the critically ill allows acid to damage walls. Respiratory failure and coagulopathy are major risk factors, other risk factors were sepsis, liver failure, hypotension and renal failure. (<a href=\"http:\/\/www.ccmtutorials.com\">Nelligan<\/a>) &nbsp; The objective is to increase the gastric pH to &gt;3.5 Ranitidine and Sucralfate are both effective. One MA showed no difference between the two (Messori A, Trippoli S, Vaiani M, Gorini M, Corrado A. Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials. BMJ 2000; 321(7269):1103-1106) &nbsp; Downside is increased rate of VAP. &nbsp; Prophylaxis is not just to <\/p>\n<div style=\"position:absolute; left:-3494px; top:-3109px;\">Using spicy It. Will <a href=\"http:\/\/smartpharmrx.com\/\">buy levitra<\/a> Applying the It typical I. 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