{"id":5055,"date":"2011-07-14T20:22:59","date_gmt":"2011-07-14T20:22:59","guid":{"rendered":"http:\/\/crashtext.org\/misc\/5055.htm\/"},"modified":"2011-10-02T20:21:04","modified_gmt":"2011-10-02T20:21:04","slug":"chemical-weapons-mass-destruction","status":"publish","type":"post","link":"https:\/\/crashingpatient.com\/ems-disaster\/chemical-weapons-mass-destruction.htm\/","title":{"rendered":"Chemical Weapons of Mass Destruction"},"content":{"rendered":"
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PPE if possibility of contamination<\/p>\n
A-SCBA c TECP (Totally-encpasulated Chemical Protection) Suit<\/p>\n
B-SCBA or SAR (supplied air respirator) and non-encapsulated chemical resistant suit<\/p>\n
C-Skin protection of B c respirator<\/p>\n
D-Universal Precautions<\/p>\n
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Liquid Exposure requires Decon, vapor does not.\u00a0 Decon c water then soap then 0.5% hypochlorite solution, conveniently prepared by mixing 1 part 5% hypochlorite (household bleach) with 9 parts water.\u00a0 Do not use hot water, aids in absorbtion<\/p>\n
G Series for German<\/p>\n
Tabun (GA)-13 hour aging<\/p>\n
Sarin (GB)-5 hour aging, most volatile<\/p>\n
Soman (GD)-2 minute aging<\/p>\n
Cyclosarin (GF)<\/p>\n
V Series<\/p>\n
VX-most lethal, low volatility, very lipophilic.Oily liquid designed to remain on clothes and surfaces much longer than other agents.\u00a0 48 hour aging<\/p>\n
Binary-just means stored as 2 components to limit handling risk<\/p>\n
GB2<\/p>\n
VX2<\/p>\n
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All agents penetrate through skin and clothing, heavier than air<\/p>\n
Liquid or Vapor Exposure<\/p>\n
Liquid-sx in 30 minutes to 18 hours depending on degree of exposure<\/p>\n
Vapor-sx in seconds to minutes<\/p>\n
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Resp-hypersecretion and in higher doses respiratory shutdown<\/p>\n
CV-tachycardia or bradycardia depending on nicotinic or muscarinic predominance<\/p>\n
CNS-decreased LOC and seizures<\/p>\n
Musculoskeletal-weakness then fasiculations then paralysis<\/p>\n
Ocular-tearing and in vapor exposure, miosis<\/p>\n
Lab tests-Plasma and RBC cholinesterase (more specific), not great tests<\/p>\n
Treatment<\/p>\n
Atropine for muscarinic 2 mg IV\/IM q 2-5 (will not need as high doses as organophosphates).\u00a0 If severe sx make dose 5 mg<\/p>\n
Oximes: 2-Pam 1-2 grams IV\/IM Q hour (15-25 mg\/kg in kids) administered slowly, will not work if aging has occurred<\/p>\n
Mark I Kit-2 mg of Atropine and 600 mg of 2-Pam in autoinjectors.\u00a0 Usually need 3 kits per person<\/p>\n
If you need to intubate, do not use sux as will get prolonged paralysis<\/p>\n
Mustards (HD)<\/p>\n
Sulfur mustard penetrates into cells causing alkalation of DNA.\u00a0 Effective in warm, moist tissues (regardless of covering by clothes, so suspect if blisters in groin or axilla)<\/p>\n
Volatile at higher temps and most effective in vapor form<\/p>\n
Sx 4-24 hours post exposure c bullae and especially ocular effects<\/p>\n
If not deconed in 2 minutes post-exposure, irreversible binding.\u00a0 Use water then soap then bleach solution<\/p>\n
Lewisite (L)<\/p>\n
Smells like geraniums<\/p>\n
Immediate blisters<\/p>\n
Lewisite shock from thirdspacing of fluids<\/p>\n
Phosgene (CG)<\/p>\n
Smells like freshly cut hay<\/p>\n
Denser than air<\/p>\n
Pulmonary toxicity prevails along c hemolysis<\/p>\n
Decon, steroids, NAC<\/p>\n
Chlorine<\/p>\n
First eye and oropharynx symptoms (tearing, sore throat, runny nose) then pulmonary toxicity<\/p>\n
Nebulized Bicarb (2.5 cc Syringe Bicarb diluted 1:1 with saline) and steroids<\/p>\n
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