Urine Testing
Drug
Acute Use
Chronic Use
Amphetamines
1 day
Weeks
Barbs
Short one day
Long 2-3 weeks
Benzos
3 days
4-6 weeks
Cocaine
2-3 days
4-6 days
Codeine/Morphine
2-4 days
4-6 days
Methadone
2-3 days
1-2 weeks
PCP (DM false +)
Up to 1 week
1-2 weeks
Propoxyphene
1-2 days
Several days
Marijuana
Single use: 4 days
Moderate : 10 days
Heavy Use: 4-6 weeks
Passive Inhalation: neg
Nicotine
1-2 days
From Quest Diagnostics
Hallucinogens
The term pyachedelic is from the name of an album by a Texan band, the Psychedelic Sounds of the 13th Floor Elevators
Lysergic Acid Diethylamide (LSD)
Lyserge Saure Diethylamid
Mescaline
from peyote or cactus
Psilocybin Mushrooms
Morning Glory Seeds
Ergot
from Rye and wheat
LSD like compounds
Bufotoxins
From licking toads
Jimson Weed
Anticholinergic poisoning
CoricidinHBP Cold and Flu 325 mg acetaminophen, 2 mg chlorpheniramine maleate; (2) CoricidinHBP Cough and Cold 30 mg dextromethorphan HBr, 4 mg chlorpheniramine maleate; and (3) CoricidinHBP Maximum Strength Flu 500 mg acetaminophen, 15 mg dextromethorphan HBr, 2 mg chlorpheniramine maleate
Dextromethorphan is a common antitussive agent found in many OTC cough and cold preparations. It is the d-isomer of 3-methoxy-N-methylmorphine, a synthetic analogue of codeine. Dextromethorphan antagonizes N-methyl-D-aspartate (NMDA) glutamate receptors and inhibits the reuptake of serotonin. These effects could account for the acute and chronic abuse potential. Symptoms of mild intoxication include tachycardia, miosis or mydriasis, ataxia, clumsiness, hyperexcitability, nystagmus, restlessness, hallucinations, and dystonic reactions. Severe poisoning can result in stupor, coma, seizures, toxic psychosis, and respiratory depression.[4 and 5] Naloxone has been reported to be an effective antidote in some cases. [6]
Chlorpheniramine maleate is an H1-receptor antagonist. Overdose results in anticholinergic toxicity: warm, dry, and flushed skin, mydriasis, dry mouth, delirium, tachycardia, gastrointestinal dysmotility, and urinary retention. Seizures, hyperthermia, and rhabdomyolysis have been reported in severe cases of chlorpheniramine ingestion.[7 and 8] In pure antihistamine overdoses with life-threatening anticholinergic symptoms, physostigmine has been used as an effective antidote. [9]
Acetaminophen is a common analgesic and antipyretic found in over 100 OTC cold preparations. It is the most common analgesic implicated in reported cases of poisonings.[1] Therapeutic ingestions are easily handled by glutathione detoxification in the liver, but in overdoses the glutathione capacity is overwhelmed by the toxic metabolite n-acetyl-p-benzoquinonemine (NAPQI). Initial symptoms are usually mild and nonspecific, and evidence of hepatic toxicity is delayed by 2448 hours postingestion. The antidote N-acetylcysteine (NAC) is virtually 100% hepatoprotective when initiated within 8 hours of an acute overdose. [10]
Adolescent abuse of dextromethorphan cough syrups for a phencyclidine-type “high” has been well described.[6] Although cough syrups have traditionally been the preparation of choice among adolescents, the convenience of the tablet form of Coricidin has made it increasingly popular. [11] One tablet contains the equivalent of 3 teaspoons (15 mL) of dextromethorphan syrup. The additional euphoric properties associated with the anticholinergic properties of the chlorpheniramine in CoricidinHBP tablets make it a favored OTC product, over dextromethorphan syrup alone, among young adults. [11, 12 and 13]
The American Journal of Emergency Medicine Volume 21, Issue 6 , October 2003, Pages 473-475
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