Lipid Rescue

Caution with interpreting laboratory results after lipid rescue therapy. Punja M et al. Am J Emerg Med 2013 Aug 8 [From the Excellent Poison Review] No abstract available This short case report from Emory University and the Georgia Poison Center makes the point that administering lipid rescue therapy (LRT) may affect laboratory results in ways that […]

Extracorporeal Removal Techniques in Toxicology

From (J Intensive Care Med 2012;25(3):139) Characteristics of Xenobiotics That Are Cleared by ECR For all 3 techniques Low volume of distribution (Vd; <1 L/kg), that is, not in tissue Single-compartment kinetics Low endogenous clearance (<4 mL/min per kilogram) For hemodialysis MW <500 Da (little data on high-flux membranes) Water soluble No plasma protein binding […]

Bath Salts

This class of drugs are chemically altered hallucinogenic stimulants. Depending on which chemical is used in the salts, the patient can look like they took meth or ecstasy. They will present with a sympathomimetic toxidrome including hyperadrenergic vitals and profound hyperthermia. Here is a link to Leon’s Gussow’s bath salt article in EM News. Scott […]